PRO Gel 5000 Toothpaste with Nano-Hydroxyapatite
Dentist-developed and made in the USA – Professional Exclusive Product
The remineralizing toothpaste you’ve been waiting for! It is the only toothpaste to include a unique combination of 1.1% fluoride and nano-hydroxyapatite (nanoXIM) for superior remineralization. Our soothing low-abrasion formulation also utilizes our patented elevated pH technology to neutralize acids. The benefits of this gel are unlike any other!
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PRO Gel 5000 Toothpaste with Nano-Hydroxyapatite
2.4 oz tube (approximately 136 doses), recommended for ages 6+, and made in the USA!
- Mild and moistening for dry mouth
- Proudly contains nanoXIM by FLUIDINOVA, the only nano-hydroxyapatite globally recognized and approved for oral care by the European Scientific Committee on Consumer Safety
- 1.1% Sodium Fluoride
- 25% Xylitol
- Elevated pH technology
- Low abrasion (RDA 40)
Use once daily as your normal dentifrice or as directed by your dental professional. Apply a thin ribbon of gel dentifrice to toothbrush and brush thoroughly on all tooth surfaces for at least one minute. Adults, expectorate gel after use and for best results do not eat, drink or rinse for 30 minutes. Adolescent patients, ages 6-17, expectorate after use and rinse mouth thoroughly. Instruct children under 12 to minimize swallowing. Supervise children as necessary until capable of using without supervision.
MINT
Active Ingredient: Sodium Fluoride, 1.1% (w/w); Other Ingredients: Glycerin, Hydrated Silica, Hydrogenated Starch Hydrolysate (HSH), Hydroxyapatite, Hydroxyethyl Cellulose, Menthol, Natural Flavors, Polysorbate 20, Potassium Sorbate, Saccharin, Sodium Benzoate, Sodium Bicarbonate, Sodium Hydroxide, Sodium Lauryl Sulfate, Water, Xylitol
CITRUS
Active Ingredient: Sodium Fluoride, 1.1% (w/w); Other Ingredients: Glycerin, Hydrated Silica, Hydrogenated Starch Hydrolysate (HSH), Hydroxyapatite, Hydroxyethyl Cellulose, Natural and Artificial Flavors, Polysorbate 20, Potassium Sorbate, Saccharin, Sodium Benzoate, Sodium Bicarbonate, Sodium Hydroxide, Sodium Lauryl Sulfate, Water, Xylitol
How well does the CariFree Gel 5000 remineralize?
A recent 2022 study has shown the CariFree PRO Gel 5000 achieved a 63% surface microhardness recovery in just three days. This is particularly impressive when compared to a similar study where a high fluoride control toothpaste, also with 5000 ppm fluoride, achieved a 33.5% recovery, but over a longer period of 10 days.
Why do you use Fluoride with nano-hydroxyapatite instead of n-HA alone?
Fluoride and nano-hydroxyapatite together create fluorapatite, which is more resistant to demineralization, a huge bonus when the goal is cavity prevention.
How much nano-hydroxyapatite is in your gel?
While we don’t release final concentrations of our formulas, our company focuses on quality and size, as studies show that the most bioavailable size of nano-hydroxyapatite particles are 20 nanometers, and rod-shaped particles are the safest and vital for remineralization. Our gels use high-grade, rod-shaped particles that present a length of <50nm and width of <10nm to ensure effective remineralization. Since 2012, we have used nanoXIM by FLUIDINOVA in our products, the only nano-hydroxyapatite globally recognized and approved for oral care by the European Scientific Committee on Consumer Safety.
How is your 5000 ppm toothpaste different from other 5000 ppm toothpastes?
CariFree Gel 5000 is the only prescription-strength toothpaste that also contains nano-hydroxyapatite.
How effective is the Gel 5000 at changing the pH in a patient's mouth?
pH is the central component of all CariFree products. In a recent study completed by Intertek, it was found that the “CariFree Pro Gel 5000 toothpaste formulation was able to buffer pH of dental plaque and prevent pH drops to pH levels associated with enamel damage.
PRO Gel 5000 Intertek Lab pH Study
“CariFree PRO Gel 5000 toothpaste demonstrated effective pH buffering capabilities in dental plaque, maintaining a range crucial for enamel remineralization during a 20-minute sucrose challenge. This performance indicates the toothpaste’s potential to create an oral environment that favors remineralization and counters the acidogenic effects typically induced by sugar intake.”
PRO Gel 5000 Intertek Lab Remineralization Study
“CariFree PRO Gel 5000 achieved a 63% surface microhardness recovery in just three days. This is particularly impressive when compared to a similar study where a high fluoride control toothpaste, also with 5000 ppm fluoride, achieved a 33.5% recovery, but over a longer period of 10 days.”
PRO Gel 5000 Indiana University RDA Study
Hara, A. T., & Ding, R. (2024). Final report: Determination of the relative dentin abrasion level of dentifrices (Report No. 24-RDA-104). Indiana University School of Dentistry, Oral Health Research Institute.
The study concluded that the PRO Gel 5000 has an RDA of 48.9 +/- 1.02.